Dutch Annual Virology Symposium (DAVS)

Opening and presentations 1: five speakers (80 min.) 

Convenor: Raoul de Groot 

• Anais Wiech 

The Role of Varicella-Zoster Virus pVLT-ORF63 and pORF63 in Modulating Host Chromatin During Lytic Infection  (15+ 5 min) 

• Meryl Haas 

Structure of the Human Norovirus NTPas; (15+ 5 min) 

• Joost Snijder  

Direct mass-spectrometry based sequencing and repertoire profiling of anti-RSV-F antibodies from human serum (15+ 5 min) 

• Mark Bakkers  

pitch; A foldon-free prefusion F trimer vaccine for RSV to reduce off-target immune responses (5+ 3 min) 

• Haye Nijhuis 

pitch: Producing and stabilizing recombinant surface glycoproteins from highly pathogenic zoonotic viruse (5+ 3 min) 

10.55 a.m. Coffee & tea break + postersessions (35 min.)

Presentations 2: five speakers (80 min.) 

Convenor: Jolanda Smit 

• Oscar Lezcano 

Recurrent selection of 2B mutations in an insect picornavirus upon experimental evolution in a nonnative host (15+ 5 min) 

• Wessel Willemsen 

Differential effect of acute versus persistent insect-specific flavivirus infection on superinfection exclusion of Zika virus (15+ 5 min) 

• Sebastian Lequime  

Incorporating empirical lab data into epidemiological risk assessments: taking into account host heterogeneity and within-host dynamics (15+ 5 min) 

• José Dekker  

pitch: HIV-1 can escape from dolutegravir inhibition through mutations that cause integration-independent virus replication (5+ 3 min) 

• Thibault Mesplede  

pitch: Rapid selection of HIV 3’PPT mutations in the presence of integrase strand transfer inhibitors ((5+ 3 min) 

12.50 p.m. Lunch break + poster session (70 min.)

Presentations 3: five speakers (80 min.) 

Convenor: Sander Herfst 

• Salina Quack  

MDA5 employs ATP hydrolysis to condense long dsRNA into a stable nucleoprotein complex (15+ 5 min) 

• Lisa Bauer  

Increased attachment to, and replication of recent avian H5N1 influenza A viruses from clade 2.3.4.4b in human airway epithelial cells  (15+ 5 min) 

• Huib Rabouw 

Dissecting the Influenza A virus infection cycle through single vRNP imaging (15+ 5 min) 

• Willemijn Rijnink 

pitch: A novel antigenically central HA mRNA vaccine confers humoral and cellular immune responses and protects ferrets against challenge with a heterologous A(H5) clade 2.3.4.4b highly pathogenic avian influenza virus (5+ 3 min) 

• Annelies de Rooij   

pitch: Long term evolution of seasonal influenza A/H3N2 virus in differentiated human airway epithelial pathways reveals diverse evolutionary potential (5+ 3 min) 

3.20 p.m. coffee & tea break + poster session (40 min.) 

Beijerink Awards Ceremony + short lectures (75 min.)  

Convenor: Monique van Oers 

• Marileen Dogterom 

Welcome by President of the KNAW 

• Marc Bonten 

Laudations by Chair of the Advisory Committee M.W. Beijerinck Virology Fund  

• John van der Oost

M.W. Beijerinck Virology Award Lecture

• Puck van Kasteren
• Carmen Embregts  

Presentations of the Beijerinck Premium Recipients

5.15 p.m. drinks and bites